Hanno L Tan Selected Research

Ajmaline (Wolfina)

1/2021	Left Axis Deviation in Brugada Syndrome: Vectorcardiographic Evaluation during Ajmaline Provocation Testing Reveals Additional Depolarization Abnormalities.
1/2020	Sudden cardiac death in families with premature cardiovascular disease.
10/2019	Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores.
12/2017	Yield and Pitfalls of Ajmaline Testing in the Evaluation of Unexplained Cardiac Arrest and Sudden Unexplained Death: Single-Center Experience With 482 Families.
8/2010	Liquid chromatographic assay with fluorescence detection to determine ajmaline in serum from patients with suspected Brugada syndrome.
2/2010	Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation.
1/2010	Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch.

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Hanno L Tan Research Topics

Disease

23	Brugada Syndrome 05/2022 - 03/2004
19	Out-of-Hospital Cardiac Arrest 03/2024 - 05/2011
16	Cardiac Arrhythmias (Arrythmia) 10/2019 - 06/2005
8	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2023 - 06/2014
6	Heart Failure 01/2023 - 11/2005
5	Long QT Syndrome 10/2013 - 06/2005
5	Pulmonary Hypertension 01/2010 - 09/2006
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 01/2020
4	Heart Diseases (Heart Disease) 01/2022 - 05/2006
3	Mood Disorders (Mood Disorder) 01/2021 - 10/2020
3	Ventricular Tachycardia 11/2020 - 05/2013
3	Bradycardia 01/2020 - 06/2005
3	Atrial Fibrillation 11/2018 - 01/2008
3	Channelopathies 07/2010 - 03/2009
2	Sudden Death 01/2023 - 07/2008
2	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2021
2	Disease Susceptibility (Diathesis) 05/2022 - 01/2022
2	Epilepsy (Aura) 01/2022 - 01/2015
2	Heart Arrest (Cardiac Arrest) 01/2021 - 12/2017
2	Major Depressive Disorder (Major Depressive Disorders) 11/2020 - 10/2020
2	Schizophrenia (Dementia Praecox) 01/2019 - 06/2014
2	Ventricular Fibrillation 11/2017 - 08/2012
2	Inflammation (Inflammations) 11/2010 - 07/2010
2	Necrosis 11/2010 - 07/2010
2	Disease Progression 01/2010 - 08/2009
2	Fibrosis (Cirrhosis) 08/2009 - 10/2008
2	Torsades de Pointes (Torsade de Pointes) 01/2008 - 03/2002
1	Coronary Disease (Coronary Heart Disease) 01/2023
1	Hypertension (High Blood Pressure) 01/2021
1	Mental Disorders (Mental Disorder) 10/2020
1	Social Phobia 10/2020
1	Panic Disorder (Panic Attack) 10/2020
1	Anxiety Disorders (Anxiety Disorder) 10/2020
1	Dysthymic Disorder 10/2020
1	Psychotic Disorders (Schizoaffective Disorder) 01/2020
1	Atrioventricular Block 01/2020
1	Genetic Risk Score 10/2019
1	Congenital Heart Defects (Congenital Heart Defect) 03/2019
1	Coronary Artery Disease (Coronary Atherosclerosis) 11/2018
1	Diabetic Neuropathies (Diabetic Neuropathy) 01/2018
1	Myocardial Ischemia (Ischemic Heart Diseases) 11/2017
1	ST Elevation Myocardial Infarction 11/2017
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 08/2017
1	Myocardial Infarction 01/2017
1	Paroxysmal ventricular fibrillation 04/2016

Drug/Important Bio-Agent (IBA)

16	Sodium Channels (Sodium Channel)IBA 05/2022 - 06/2005
7	Ajmaline (Wolfina)FDA Link 01/2021 - 01/2010
6	SodiumIBA 01/2022 - 05/2006
6	Sodium Channel BlockersIBA 01/2021 - 08/2006
4	Advanced Glycation End ProductsIBA 01/2021 - 01/2020
4	Flecainide (Tambocor)FDA LinkGeneric 02/2015 - 03/2004
4	MonocrotalineIBA 02/2011 - 09/2006
3	Syntex adjuvant formulationIBA 01/2021 - 10/2020
3	Proteins (Proteins, Gene)FDA Link 07/2010 - 08/2009
2	Opioid Analgesics (Opioids)IBA 01/2023 - 01/2022
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2022 - 01/2015
2	Anti-Arrhythmia AgentsIBA 01/2022 - 01/2008
2	Cardiovascular AgentsIBA 01/2022 - 03/2013
2	Ion Channels (Ion Channel)IBA 11/2020 - 01/2019
2	Amsacrine (AMSA)IBA 01/2020 - 11/2017
2	PotassiumIBA 11/2017 - 10/2013
2	Interleukin-6 (Interleukin 6)IBA 09/2015 - 11/2010
2	CytokinesIBA 09/2015 - 11/2010
2	Bosentan (Tracleer)FDA Link 01/2010 - 05/2009
2	Endothelin-1 (Endothelin 1)IBA 01/2010 - 05/2009
2	Ether (Diethyl Ether)IBA 07/2008 - 12/2005
1	SolutionsIBA 03/2024
1	omega-Chloroacetophenone (Mace)IBA 01/2023
1	Antidepressive Agents (Antidepressants)IBA 01/2022
1	Mirtazapine (Rexer)FDA LinkGeneric 01/2022
1	Citalopram FDA LinkGeneric 01/2022
1	Carbamazepine (Tegretol)FDA LinkGeneric 01/2022
1	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021
1	HDL CholesterolIBA 01/2021
1	Nifedipine (Adalat)FDA LinkGeneric 11/2020
1	DihydropyridinesIBA 11/2020
1	NitratesIBA 11/2020
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2020
1	Silver Sulfadiazine (SSD)FDA LinkGeneric 01/2019
1	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2019
1	Succinylcholine (Suxamethonium Chloride)FDA LinkGeneric 01/2019
1	LipidsIBA 11/2018
1	Lidocaine (Xylocaine)FDA LinkGeneric 01/2018
1	Antihypertensive Agents (Antihypertensives)IBA 11/2017
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 08/2017
1	Illicit Drugs (Recreational Drugs)IBA 08/2017
1	Amphetamine (Amfetamine)FDA LinkGeneric 08/2017
1	ProcalcitoninIBA 09/2015

Therapy/Procedure

8	Resuscitation 01/2023 - 05/2011
5	Defibrillators (Defibrillator) 01/2023 - 11/2011
4	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 03/2024 - 11/2008
4	Therapeutics 07/2010 - 08/2005
3	Cardiopulmonary Resuscitation (CPR) 01/2023 - 01/2019
2	Drug Therapy (Chemotherapy) 09/2014 - 03/2002
2	Endarterectomy (Thromboendarterectomy) 01/2010 - 04/2007
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2017
1	Electrodes (Electrode) 12/2015
1	Thoracotomy 11/2015